Background: Anxiety and depression are the most important factors on the quality of life in patients after coronary angioplasty. These patients have less capability for adjusting themselves with changes in life style, diet, medication and physical activity adherence. This study aimed to determine predictive factors of anxiety and depression in patients undergoing coronary angioplasty. 
Methods: In this descriptive cross-sectional study, 148 patients were selected by convenience sampling method. Data were collected by a 2-section questionnaire, including sociodemographic factors and the hospital anxiety and depression scale. Multivariate logistic regression was used to determine predictors of anxiety and depression. Using a convenience sampling method, the patients were selected among those patients undergoing PCI in Heshmat Heart Medical Hospital in Rasht, Iran between March 2015 and June 2015. Analyses were performed using SPSS 19.
Results: The majority of samples were male (61.5%), married (93.2%), retired (31.1%), and illiterate (48%). Their mean (SD) age was 60.02(10.5) years. According to the findings, 62.2% suffered from clinical anxiety and 20.3% suffered from clinical depression. The results of multivariate adjusted model showed that education level is significantly associated with mild depression. Also sex and age are significant predictors for severe depression. Male patients were less likely to have severe depression compared to female ones . Middle age patients (45-64 years) compared to older adults were more likely to be diagnosed with severe depression.
Conclusion: Considering the high prevalence of anxiety and depression symptoms in these patients, they need counseling, social and psychological support before, during and after procedures such as angioplasty.