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Volume 10, Issue 4 (Autumn - In Press 2024)
JCCNC 2024, 10(4): 7-7 |
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Zarabadi-pour S, Eghbali M, Amini L, Nabavi S M, Haghani H, Avval Shahr H S. The Effects of Vitamin D Supplementation on the Sexual Function and Sex Hormones in Women with Multiple Sclerosis: A Randomized Controlled Clinical Trial. JCCNC 2024; 10 (4) :7-7
URL: http://jccnc.iums.ac.ir/article-1-554-en.html
URL: http://jccnc.iums.ac.ir/article-1-554-en.html
Simin Zarabadi-pour * 
1, Mohammad Eghbali2 , Leila Amini3 , Seyed Massood Nabavi4 , Hamid Haghani5 , Homa Sadeghi Avval Shahr6
1, Mohammad Eghbali2 , Leila Amini3 , Seyed Massood Nabavi4 , Hamid Haghani5 , Homa Sadeghi Avval Shahr6
1- Master of Midwifery Education, School of Nursing and Midwifery, Iran University of Medical Sciences
2- Assistant Professor of Nursing, School of Nursing and midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
3- Reproductive Health, Nursing Care Research Center (NCRC), Associate Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
4- Neurologist, Department of Neurology and Cognitive Science Research Institute of Cellular Sciences, Royan Research Center, Tehran, Iran
5- Department of biostatistics, Iran University of Medical Sciences, Tehran, Iran
6- Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
2- Assistant Professor of Nursing, School of Nursing and midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
3- Reproductive Health, Nursing Care Research Center (NCRC), Associate Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
4- Neurologist, Department of Neurology and Cognitive Science Research Institute of Cellular Sciences, Royan Research Center, Tehran, Iran
5- Department of biostatistics, Iran University of Medical Sciences, Tehran, Iran
6- Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
Abstract: (297 Views)
Background: Sexual dysfunction is the most common and challenging complication among women with multiple sclerosis (MS). Despite investigations into the impact of taking vitamin D on sexual function (SF), research findings have not definitively recommended its use. This study aimed to evaluate the effects of vitamin D supplementation on SF and sex hormones among women with MS.
Methods: This triple-blind, randomized, placebo-controlled clinical trial was conducted on 62 married women with MS and vitamin D deficiency successively recruited from a specialized clinic for neurology in Tehran, Iran, between August 2017 and February 2018. The subjects were randomly allocated to either experimental or control group (n=31/each group). Subjects in the experimental and control groups received two 2000-IU vitamin D and two placebo tablets per day for 12 consecutive weeks, respectively. Serum levels of sex hormones and their SF were evaluated before and after the intervention. The SF assessment was performed using the Female Sexual Function Index (FSFI). Data were analyzed using independent-sample t-test, paired t-test, Fisher’s exact test, Mann-Whitney-U test and Chi-square in SPSS software (v. 22.0). The level of significance was determined at lower than 0.05.
Results: The findings revealed no significant difference between the two groups in terms of sex hormones, level of Vitamin D and SF before intervention. The study results indicated that taking vitamin D supplementation for 12 weeks significantly impacts the improvement of SF and sex hormones (P<0.05).
Conclusion: Twelve weeks’ consumption of vitamin D supplementation may improve sexual function and sex hormones among women with MS.
Methods: This triple-blind, randomized, placebo-controlled clinical trial was conducted on 62 married women with MS and vitamin D deficiency successively recruited from a specialized clinic for neurology in Tehran, Iran, between August 2017 and February 2018. The subjects were randomly allocated to either experimental or control group (n=31/each group). Subjects in the experimental and control groups received two 2000-IU vitamin D and two placebo tablets per day for 12 consecutive weeks, respectively. Serum levels of sex hormones and their SF were evaluated before and after the intervention. The SF assessment was performed using the Female Sexual Function Index (FSFI). Data were analyzed using independent-sample t-test, paired t-test, Fisher’s exact test, Mann-Whitney-U test and Chi-square in SPSS software (v. 22.0). The level of significance was determined at lower than 0.05.
Results: The findings revealed no significant difference between the two groups in terms of sex hormones, level of Vitamin D and SF before intervention. The study results indicated that taking vitamin D supplementation for 12 weeks significantly impacts the improvement of SF and sex hormones (P<0.05).
Conclusion: Twelve weeks’ consumption of vitamin D supplementation may improve sexual function and sex hormones among women with MS.
Type of Study: Research |
Subject:
Special
Received: 2023/11/20 | Accepted: 2024/04/30 | Published: 2024/08/20
Received: 2023/11/20 | Accepted: 2024/04/30 | Published: 2024/08/20
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