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Volume 10, Issue 4 (Autumn - In Press 2024)
JCCNC 2024, 10(4): 8-8 |
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Norouzi M, Amiri Z, sadeghi M, Neshat Iranpour M, Taghipour A, Khosravi Asl T et al . Frailty as a Predictor of Mortality in Elderly Iranians Residing in Nursing Home Facilities: A Retrospective Cohort Study. JCCNC 2024; 10 (4) :8-8
URL: http://jccnc.iums.ac.ir/article-1-580-en.html
URL: http://jccnc.iums.ac.ir/article-1-580-en.html
Mehdi Norouzi 
, Zahra Amiri , Masoumeh Sadeghi , Mohaddese Neshat Iranpour , Ali Taghipour , Tahere Khosravi Asl , Ehsan Mosafarkhani *
, Zahra Amiri , Masoumeh Sadeghi , Mohaddese Neshat Iranpour , Ali Taghipour , Tahere Khosravi Asl , Ehsan Mosafarkhani *
Abstract: (415 Views)
Background: Frailty is a common geriatric syndrome associated with adverse health outcomes in the elderly. This study aimed to examine the association between frailty index and mortality in elderly residents of nursing homes in Iran.
Methods: This historical cohort study used data extracted from the Sina Electronic Health Record System (SinaEHR®, Iran) and national cause of death registry in Iran. The study population included 9,199 adults aged ≥60 years who were assessed for frailty in nursing homes across Iran from April 2021 to June 2022. and were followed up until August 2022. Frailty was defined as a score >3 on the Fried’s five-item index. Multivariable logistic regression analysis determined adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for factors associated with mortality. Chi-square tests compared mortality across groups. Data were analyzed using Stata version 11 with p<0.05 as the significance level.
Results: Of 9,199 subjects, 3,566 (38.7%) were frail and 5,643 (61.3%) were non-frail. During follow-up, 3,354 (36.5%) deaths occurred. Frailty was associated with 2.49 times higher odds of mortality (95% CI 2.27-2.74, p<0.001) compared to non-frail state after adjustment for covariates. Older age (p<0.001), female sex (p<0.001), and comorbidities (p<0.001) were also significant predictors of mortality.
Conclusion: Frailty index strongly predicts mortality risk in Iranian elderly nursing home residents. Assessing and managing frailty may help reduce adverse outcomes in this vulnerable population.
Methods: This historical cohort study used data extracted from the Sina Electronic Health Record System (SinaEHR®, Iran) and national cause of death registry in Iran. The study population included 9,199 adults aged ≥60 years who were assessed for frailty in nursing homes across Iran from April 2021 to June 2022. and were followed up until August 2022. Frailty was defined as a score >3 on the Fried’s five-item index. Multivariable logistic regression analysis determined adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for factors associated with mortality. Chi-square tests compared mortality across groups. Data were analyzed using Stata version 11 with p<0.05 as the significance level.
Results: Of 9,199 subjects, 3,566 (38.7%) were frail and 5,643 (61.3%) were non-frail. During follow-up, 3,354 (36.5%) deaths occurred. Frailty was associated with 2.49 times higher odds of mortality (95% CI 2.27-2.74, p<0.001) compared to non-frail state after adjustment for covariates. Older age (p<0.001), female sex (p<0.001), and comorbidities (p<0.001) were also significant predictors of mortality.
Conclusion: Frailty index strongly predicts mortality risk in Iranian elderly nursing home residents. Assessing and managing frailty may help reduce adverse outcomes in this vulnerable population.
Type of Study: Research |
Subject:
Special
Received: 2024/01/22 | Accepted: 2024/04/30 | Published: 2024/08/20
Received: 2024/01/22 | Accepted: 2024/04/30 | Published: 2024/08/20
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