Background: The prevalence of Diabetes Mellitus (DM) is increasing, especially in low- middle-income countries. DM leads to changes in blood sugar, cholesterol and viscosity. Therefore, seeking alternative medicine with active ingredients to lower blood sugar levels, cholesterol, and blood viscosity is crucial. This study analyzed the effect of Red Ginger Extract and Klanceng Honey on Sugar Levels, Cholesterol, and Blood Viscosity among diabetic patients with hyperglycemia and hypercholesterolemia in Pekalongan City, Central Java, Indonesia.
Methods: This was a quasi-experimental study with pre-test and post-test design. The subjects were diabetic patients with hyperglycemia and hypercholesterolemia. Thirty participants were randomly assigned to three groups (ginger group, honey group, and combination of ginger and honey group), each with ten subjects. The dosage of Red Ginger Extract was 60 mg/day, while for klanceng honey, the dose was 1 ml / Kg body weight/day. The subjects consumed ginger extract 3-4 capsules, Klanceng honey 15-20 ml (considering their weight), or a combination of ginger and Klanceng three times a day for seven consecutive days. SPSS version 22 was used to analyse the data. Bivariate and mathematical General Linear Models (GLM) were applied with the significance level of 0.05 .
Results: The combination of red ginger and Klanceng Honey significantly reduced blood sugar levels (p=0.001, CI 95%= 10.20-28.80), cholesterol (p < 0.001, CI 95%= 9.44 - 25.16), and blood viscosity (p < 0.001, CI 95%= 1.63 - 3.17) compared to giving Klanceng Honey or Red Ginger alone. A mathematical General Linear Model (GLM) analysis, controlling for pre-treatment blood values, showed that the combination of red ginger and Klanceng honey reduced blood sugar by 6.89% compared to Klanceng honey and 0.01% compared to red ginger alone. It also lowered cholesterol by 4.00% compared to Klanceng honey and 1.50% compared to red ginger alone. The combination of red ginger and Klanceng honey also reduced viscosity by 3.98% compared to Klanceng honey and by 1.53% compared to red ginger alone.
Conclusion: The combination of red ginger extract and klanceng honey was more effective in reducing blood sugar, cholesterol, and blood viscosity than only the Klanceng honey and red ginger extract. People with hyperglycemia and hyperlipidemia may use the combination of Red Ginger Extract and Klanceng Honey to regulate blood sugar, cholesterol, and viscosity. Healthcare providers may recommend this complementary therapy for such patients. Further studies with larger sample sizes and longer treatment periods may be useful to obtain more precise results.
نوع مطالعه:
پژوهشي |
موضوع مقاله:
عمومى دریافت: 1403/8/7 | پذیرش: 1403/11/10 | انتشار: 1404/5/27