دوره 12، شماره 2 - ( 2-1405 )
جلد 12 شماره 2 صفحات 188-177 |
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Banihashemi Z, Azizi-Fini I, Rajabi M, Yadollahi S, Maghami M. Effect of Astragalus Root Extract on Anxiety and Sleep Quality in Nurses Post-COVID-19: A Randomized, Triple-blind, Placebo-controlled Trial. JCCNC 2026; 12 (2) :177-188
URL: http://jccnc.iums.ac.ir/article-1-938-fa.html
URL: http://jccnc.iums.ac.ir/article-1-938-fa.html
Effect of Astragalus Root Extract on Anxiety and Sleep Quality in Nurses Post-COVID-19: A Randomized, Triple-blind, Placebo-controlled Trial. نشریه مراقبت پرستاری مددجو محور. 1405; 12 (2) :177-188
چکیده: (588 مشاهده)
Background: Nurses on the front lines of COVID-19 have suffered many complications, including anxiety and sleep disorders. This study examined the effects of Astragalus root extract (ARE) on nurses’ anxiety and sleep quality post-COVID-19.
Methods: The study was a randomized, triple-blind, placebo-controlled trial conducted in Kashan, Iran, in 2023. Based on the quota of each department, subjects were recruited and randomly allocated to either the intervention group (n=32), who received ARE, and the control group (n=32), who received a placebo for one month. Demographic forms, the Pittsburgh sleep quality index (PSQI), and the Beck anxiety inventory (BAI) were completed by the subjects before, immediately after, and one month after the end of the intervention. Data were analyzed by descriptive statistics, independent t-tests, generalized estimating equations (GEE), chi-square tests, one-way ANOVA, and repeated measures ANOVA using SPSS 16. The significance level was set at P<0.05. The study was conducted and reported based on CONSORT guidelines for herbal medicines.
Results: A statistically significant difference was observed in the mean sleep quality score between the intervention and control groups immediately after the intervention (P=0.001) and one month later (P=0.003). Moreover, changes in the sleep quality score in the intervention group were significant over time (F=17.8, P<0.001). There was also a significant difference between the sleep quality of the two groups over time (F=5.32, P=0.006). The mean anxiety score between the two groups was significantly different immediately after the intervention (P=0.02), one month later (P=0.04), and over time (F=16.69, P<0.001). Moreover, changes in the anxiety score between the two groups showed a significant statistical difference (F=14.96, P<0.001).
Conclusion: ARE can reduce anxiety among nurses post-COVID-19 and improve the quality of their sleep.
Methods: The study was a randomized, triple-blind, placebo-controlled trial conducted in Kashan, Iran, in 2023. Based on the quota of each department, subjects were recruited and randomly allocated to either the intervention group (n=32), who received ARE, and the control group (n=32), who received a placebo for one month. Demographic forms, the Pittsburgh sleep quality index (PSQI), and the Beck anxiety inventory (BAI) were completed by the subjects before, immediately after, and one month after the end of the intervention. Data were analyzed by descriptive statistics, independent t-tests, generalized estimating equations (GEE), chi-square tests, one-way ANOVA, and repeated measures ANOVA using SPSS 16. The significance level was set at P<0.05. The study was conducted and reported based on CONSORT guidelines for herbal medicines.
Results: A statistically significant difference was observed in the mean sleep quality score between the intervention and control groups immediately after the intervention (P=0.001) and one month later (P=0.003). Moreover, changes in the sleep quality score in the intervention group were significant over time (F=17.8, P<0.001). There was also a significant difference between the sleep quality of the two groups over time (F=5.32, P=0.006). The mean anxiety score between the two groups was significantly different immediately after the intervention (P=0.02), one month later (P=0.04), and over time (F=16.69, P<0.001). Moreover, changes in the anxiety score between the two groups showed a significant statistical difference (F=14.96, P<0.001).
Conclusion: ARE can reduce anxiety among nurses post-COVID-19 and improve the quality of their sleep.
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