en تخصصي Special پژوهشي Research <div style="text-align: justify;"><strong>Background</strong>: Despite the decisive role of nurses in patient&rsquo;s education, they have limited ability to carry out this responsibility. One of the reasons for this incompetence is insufficient nursing education programs. This study aimed to compare and contrast the effects of multiple teaching methods and conventional methods on knowledge, satisfaction, and performance of bachelorette nursing students.<br> <strong>Methods</strong>: We conducted a quasi-experimental study with pre-test, post-test design. A sample of 154 nursing students from Tehran University of Medical Sciences was selected and then randomized into experimental (77) and control groups (77). The control group received conventional teaching, and the experimental group received multiple teaching methods, including scenario writing, role playing, videotaping, and analyzing, in 12 weekly sessions. The obtained data were analyzed by the Chi-square and Mann-Whitney tests in SPSS V. 18.<br> <strong>Results</strong>: Multiple teaching methods did not affect nursing students&rsquo; knowledge. However, it resulted in higher student satisfaction (P=0.001) and improved performance with regard to patient&rsquo;s education (P=0.001).<br> <strong>Conclusion</strong>: Multiple teaching methods may help students to educate, interact, communicate, and cooperate with patients more effectively.&nbsp;<span dir="RTL"></span></div> <span dir="RTL"></span> Teaching methods, Patient’s education, Nursing student, Learning outcomes 33 42 http://jccnc.iums.ac.ir/browse.php?a_code=A-10-288-1&slc_lang=en&sid=1 Fatemeh Ghaffari ghafarifateme@yahoo.com 10031947532846006396 10031947532846006396 No Nursing Care Research Center, Babol University of Medical Sciences, Babol, Iran.; Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Agha Fatemeh Hosseini Hosseini.f@iums.ac.ir 10031947532846006397 10031947532846006397 No Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. Mohammad Reza Zarei .zarei_1343@yahoo.com 10031947532846006398 10031947532846006398 No Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. Mansoureh Ashghali Farahani Farahani.ma@iums.ac.ir 10031947532846006399 10031947532846006399 Yes Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. Fatemeh Marandi 10031947532846006400 10031947532846006400 No Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.