● Pressure ulcer (PU) is one of the most serious and prevalent concerns in healthcare, and its incidence is commonly considered a marker for measuring the quality of care.
● Regarding PU prevention, in this study, the Iraqi nurses’ knowledge was low, and their attitudes and practices were unfavorable.
• The knowledge about risk assessment of PU had the lowest mean score, while the knowledge about classification and observation of PU obtained the highest score.
● Nurses’ attitudes toward the “impact of pressure ulcers” had the lowest mean score.
● Nurses considered it important to have “confidence in the effectiveness of prevention” and “prioritize pressure ulcer prevention”.
● There was a significant relationship between knowledge about PU and participation in an in-service training program on PU. 
● There was also a significant relationship between the practice of PU and years of experience in the intensive care unit.

Pressure ulcer (PU) incidence is an essential indicator of care quality. These ulcers could cause serious complications for patients, including increased morbidity and mortality rates. PU occurrence is even more prevalent among intensive care unit (ICU) patients. Given nurses’ critical role in PU prevention, evaluating their knowledge, attitude, and practice in this area is essential. This study evaluated the knowledge, attitude, and practice of ICU nurses working in Al-Basra and Dhi Qar cities, Iraq, regarding preventing PU. The findings revealed a lack of knowledge, an unfavorable attitude, and a lack of practice among nurses, emphasizing the need for targeted interventions and education to enhance PU prevention and patient care.